It went away. Zoetis claims it will be out of his system in two months and I should not see lasting effects, so I am hopeful but worried and telling everyone I know NOT to use this poison. I threw him his ball and he actually was interested in it. My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! I have already had a bad experience with "k9 advantix", so I refuse to buy over the counter drugs for my 13 week old Auggie. 4.3 4.3 out of 5 stars (34,534) $39.98 $ 39. Before he took his first doe of Simparica he was fast running, and flying through the house and yard. Conclusion One nite she ended up in emergency pet hospital they drained 1/2 liter of fluid off her and did lots of tests., wanted to put her "DOWN" With what she went thru tht day we didn't want tht to be her last day. Monday, Tuesday, Wednesday and Thursday he slept all day, was hesitant to get up, wouldn't play with his ball, continued to drink excessively and shivered. My dog was HEALTHY and HAPPY prior to giving him this drug and literally days later he is struggling to recover. It's not worth the risk of additional seizures or other neurological effects, and it seems that his stumbling and getting tired sooner on walks are likely related. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. I'm more concerned about fleas and heartworms and Trifexis is just fine for that. The American Heartworm Society recommends year-round heartworm prevention for all dogs in the United States, and the Companion Animal Parasite Council recommends broad-spectrum parasite control to prevent heartworms, intestinal parasites, fleas, and ticks for all dogs in North America. I went to banfield hospital and they prescribed this medication for my dog and had thrown up non stop since he was given the pill and wouldnt eat anything and he passed away 10 days later (yesterday). Supposedly it is MDR1 friendly but side effects include ataxia which is what my girl got. The vet said the simparica didn't cause the disease but it could have been the link that pushed him into the Crisis. I wish I read these side effects before my vet recommended Simparica Trio for my 12 week old Bichon. 5 hours after the dose she's home resting. She seems to have aged five years since T-Day. I gave my dog his first dose April 8th. We think that the drug is the cause of the seizures . It could be something else that had caused her all the pain she went through but I surely will not give my puppy Simparica anymore and I hope she is alright. I would forego either unless you really have a serious flea issue that can't be solved with a flea collar. Two days later, she is doing better, but not 100% yet. Weighing your dog regularly will ensure that you are using the correct product size. Now I have to pay $100's of dollars on meds to check her antibody and possibly put her on meds for life . Thursday morning was an awful beginning of the day for our boy. I won't be letting this go and I'll be actively pursuing recourse from the manufacturer and vet in any way I can. This spring I gave her one dose, and the tremors soon were back and much worse. He has all the symptoms Eveyone is describing. He has been eating the same organic GF food for the past several years. (On Monday, she fell down several times in an hour. The only change I could think of he started taking Simparica about 4 months ago. Bella continues to drink in excess of normal amounts. I also changed him over to a raw diet a few weeks ago too have taken him off of this again to see if raw diet is causing it. This is an eye opener for me! My dog has been on simpatico trio for 5 months .. and still got a deer tick .. She has been taking the medicine since she was 6 months and she has gotten bigger so her dosage was increased. The cardiologist found no heart condition that would cause this. This time he just kept collapsing, bloated appearing, vomit, and diarrhea, and hiding with his face down and nose in carpet. Just wanted to share my experience in case anyone else has similar experience with dog's character changing. Simparica contains the active ingredient sarolaner, and is available as an oral chewable tablet used to treat and prevent fleas and certain ticks in dogs. Is it just me or does it seem like everyone is in this together? Work up from the neurologist shows all his tests came back negative. Gave it to my dog on Thursday night and Sat stools were soft. Im at the 30 day mark from giving him the symparico and he no longer has pain but they want to continue him on a 4-6 months treatment of steroids as if its meningitis but I dont love the idea because the steroids have side effects too. Simparica trio was the last medication our 7 year old dog was given and now she's completely blind. We gave our 13 yr old lab mix this medicine as our doctor doesn't carry trifexis anymore. She seems so much happier in herself but until she comes off the keppra completely I wont know if it's a reversible problem. Sold as 1 Month, 3 Month or 6 Month Supply for the following dog weights : 2.8-5.5 lbs, 5.5-11 lbs, 11-22 lbs, 22-44 lbs, 44-88 lbs, 88-132 lbs. Im done with this drug! Still waiting to find out of she has progressed. I just wanted to get another opinion before we move forward. Today she has fallen 2 or 3 times in the last 8 hours). Today, he wouldn't eat or drink any water. Thank you in advance. Both my dogs have had runny eyes and were eating grass all summer. It is the flea and tick component that is the problem. She won't drink E walk or anything The doctor seemed to push this drug on me because the kombi guard was on back order. Do you have contact details that you can share with me. Simparica Trio is just one of many parasite prevention products on the market for dogs. Today was my 14 year old Jack Russell's 2nd dose of Simparica, her name is Rallye. Two weeks after first simparica dose.parasites gone. I just hope he has a turn around . My 3 other poodles unaffected. They still will not consider that it is the Simparica Trio. Gave my 3 month old, 3 pound shih tzu simparica on Sunday night. I gave my 15 year old dog this medicine. We did skin scrape and they kept saying allergies. I'm so sorry. I did some research and because he seemed otherwise fine, I assumed it was "small white dog" shaking due to his breed mix. It's definitely not! At the vet today, I bought a single dose of Simparica Trio to try instead of Trifexis and Combogaurd, because they seem less tolerated by her now that she is older. Simparica Trio should be given orally once a month at the recommended minimum doses: 0.54 milligrams of sarolaner, 0.011 mlilligrams of moxidectin, and 2.27 milligrams of pyrantel per pound of body weight. . Buy Simparica Trio Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 12 Chewable Tablets (12-mos. He has been on just Simparica with no problems. We are already close to $2000 in Vet bills not counting the poison we bought her. She's wobbly on her feet and seems lopsided, although her eyes look ok; she is really lethargic and barely lifting her head. I have my 14 week old pup simparica (vet recommended) 2 days ago. Sarolanerstarts fighting fleas within three hours and begins to kill ticks after 8 hoursincluding the lone star tick, black-legged tick, brown dog tick, American dog tick, and Gulf Coast tick. . In other words, they can make it easier to have a seizure in susceptible dogs. My Lab mix has had 2 doses of this med. Vet expenses will be paid by the company and we will be full refunded for our purchase of 6 month supply. We nurses him back into a happy healthy puppy and now this. How can they put something that can cause this level of damage on the market and how do vets not even tell us to monitor our pets or tell us what the risks are. Does any one think this could be a reaction to Simparico Trio? Never again are my dogs getting oral medication for fleas & ticks. Then the following week 1 pill every other day . The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. Naturally, I want to make sure that she never has to go through that again. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. He had soft poop right after I give him the pill then got worse yellow diarrhea for about a week also vomiting he fine now they changed the medication. Is there hope? Im now scared half to death. How common are Simparica side effects? He has been drinking more water then usual. 24 hours after, we noticed diarrhea. I fell like hes dying right before my hands. And a bit more stumbling. Especially after seeing these post. After her first dose she had diarrhea, vomiting and developed a terrible wheezing hacking cough. Any response from the company? I'm using milk thistle and broccoli sprout powder, and going forward I'm going to use HWF Clean Heart for heartworm prevention. While she has not had seizures, trembling, or spasms, sometimes she just squeals and jumps up for no obvious reason. Your veterinarian is the best source of information and will help you choose the right product for your dog and your budget. The vet suggested Simparico trio . Tasty, liver-flavored chewable tablet is easy to administer. I lost my previous bichon poo to seizures 2 years ago and I dont want to go through that type of pain and lost again! They want to test him for the MDR gene, put him on fluids and I have to take him in tomorrow for more fluids but he is not improving. My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. Has anyone else experienced this? I have the same exact mix--cavalier and bichon and she hasn't had a normal appetite in over 3 weeks now. I wish I read about this particular product before giving it to my dog because now I'm worried he may get more symptoms. He is disoriented, his head just hangs and he is lifeless. This was January 15 of 2020. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. like what??? I will use Sentinel and Pet Armor on her as this is what I have always gjven my dogs with no problems. She was riddled with parasites when she was found as a stray, and then treated for heartworm disease just before I adopted her. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. My 1 year old Italian Spinone puppy has been losing hair on her back and has a big ear infection. Simparica can cause ataxia, which is the official name for loss of body control. My dog steadily went downhill after I gave her the first dose of simparica. She has episodes where she seems very anxious and is hiding under car/tables/beds. Im going to keep a close watch on him over the next few days. Are there any side effects to Simparica Trio? He had kidney failure he had seizures he had nervous system problems. I looked up side effects for this drug and was horrified to find that the flea med can cause tremors seizures and worse. like she wants me to fix it. They are also drinking more than normal. Like many of you, I was unsure about the cause. If anyone has suggestions or knows how else I can help my little guy please let me know. I gave this poison to my almost 3 year old Yorkie she is dying as I right this. She is more worried about excessive thirst, lip smacking and her kidneys. So scary. Before sharing sensitive information, make sure you're on a federal government site. She has been on our property for four year and has survived everything. Its hard to say since he has previously been diagnosed with lymes. Blood work + urine sample. I want to cry I wish I could get it out of her system after reading these comments. Started in February and within a couple of weeks ears started twitching. There is a possibility it isn't the cause, but it is the only reason I can find and it aligns with the stories of others. However, doing nothing is better than giving her the Simparica. I feel like the simperica trio has somehow affected his Pituitary/Andrenal glands are maybe even acting as blockers to them. So sorry! The Simparica chewable is a poor choice for dogs with a history of prior seizures. In a weak moment last week she prescribed Simparica for a flea problem my 5 year old Springer was having. I cant believe how long this thread is. I've had to syringe water in his mouth. The issues started within 24 hours of the dose and continue. Since then I've researched loads and as you say the FDA put out a report. Thank you to all of you posting and I hope all of your babies are doing well. This morning (12/19/21) was a bit better, still hesitant on the steps but we didnt experience any loss of appetite and was eager to go outside (still some diarrhea though). Vet put her on metronidazole which is working. Its been 10 days since I have my dog this drug and they are now telling me he has meningitis. My chihuahua is 18 days since the last seizure episode, she is finally playing again but I'm noticing her shaking her head on the left side and it's very odd. The FDA has approved this product for use in dogs between 5.6 and 11 pounds 1. I would find another vet for a second opinion. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. It's important for your dog to be tested for heartworm disease before starting Simparica Trio (or any other heartworm prevention) because it will not kill adult heartworms and can actually worsen your dog's condition. After reading all your entries, i'm thrilled i chose to take her off of it. If I still lived in the city, I would probably use the garlic because the previous GS never had any issues and lived a long time. Simparica trio is a de-worming medication. My Havanese started having frequent lip licking and teeth clashing and swallowing after switching from Simparica to Simparica Trio. Hoping we dont have any more issues and will not be giving this again. A few months back he started with a morning vomiting always on his empty tummy. I hate that I did this to her and I hate that the Vet does not seem to care. Its been 3 months and she continues to have them. Hard fast shaking and terrified eyes. So from what I understand, your dog was on this for 6 months and got the serious symptoms after that? My vet never informed me of any issues with this medication and I'm kicking myself hard now after reading all of these horrible experiences with everyone's fur companions. He is otherwise normal and healthy. I was using the garlic tabs for the previous dog because the vet put him on Trifexis and he vomited like crazy. We immediately gathered her up and took her to the vet. We will have blood work and results this evening. Thank you! Gave my Olde English Bulldog puppies Simparica Trio on 4/7/21 they are almost 4 month now. Instead it has become a world of greed. In addition to the tremors, have you noticed any . I will never use this stuff again and will tell anyone I see buying it or using it my story and yours too. However, some dog parents prefer to use separate products. Is it too late? Can someone please tell me if their dogs got better after taking the pill? This is not at all his behavior. I dont know what to do to get this out of their system?? She looked it up and said they were a ton of recalls and she admitted to me that that is what possibly killed him because it was on the recalls and theyd had mini dogs come in for the same issue. I just wanted them gone and for him to feel better. My precious rescue has been sick twice, currently on her second episode. I am extremely upset at myself for letting a similar but very serious threat get to my pup again. Product Overview. Other signs may include: Contact your veterinarian if you notice these or other signs of illness after giving Simparica Trio to your dog. Company asked us to do diagnostic testing at vet. I thought it was just her aging but now I think it al started when she started this medication. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching . Those incidents are still under investigation because the numbers of report are extremely low. They did a blood test (this is literally 7 days later) and his ATL liver levels were off the charts at >2000. Don't risk the well-being of your beloved dog just because something is more convenient. Is due for another tablet but I have been holding off. I also lost my dog due to simparia Trio. Hi Charlene, can you elaborate on agitated swallowing? About 11 months ago our vet recommended Simparica Trio. My 8 month old labradoodle has had 2 doses of Simparico Trio. Shes not the carefree setter she was prior to this medication. There is NO other explanation for this rapid decline and the only change has been THIS drug. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a . If this was our children and you went to your doctor for a shot, and the Dr. said "don't worry, only 1% of kids get seizures or other problems from this shot, we wouldn't stand for it. This is apparently not true and that's why the article never goes on to explain exactly why it only works on GABA receptors in fleas and ticks yet not affect the GABA receptors in your dog. I hope I have found the culprit to his digression. Now do you get the connection? I hope this drug has not caused permanent damage. This happened the same to my dog.. how si going now with your pet? The day after administering drug he had two incapacitating seizures. She uses drops 4 times a year on the top of the neck for fleas etc and told me to address the heart worm problem with the vet. OMG - I am so mad at myself for not doing more research. I am so sorry for your loss. Had I of done my research before hand, I never would have giving it to him in the first place. I will never give my dog this medication again. around 12 years She grabs and won't let go. He just isnt himself. Consulting vet and will not give Simparica ever again. The reaction lasted less than 12 hours. Reading all of these comments I too think it is the drug that has caused his body to be toxic for him. Simparica can't be used on younger dogs or lactating dogs whereas Revolution can. I hope yours is an isolated incident! Glad i held off on the free sample i was given! I returned that medicine back to the vet and bought Revolution! Gave our pup of 10 years the Simparica Trio as suggested by our vet 1 week ago instead of the Simparica and Interceptor he had been on for 7 years with no problems. Use a collar or topical if you need to. The vet doesn't seem to really want to blame it on Simperica Trio and wants to treat these symptoms which he says are life threatening. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. Gave my 12 year old labradoodle simpatico just before going to my sons for T-Day dinner. He looked like he was having a seizure. Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. The costs associated with these two products are roughly the same. It is recommended that all pets be tested for existing heartworm infection prior to starting treatment with Simparica Trio. Wow. I'll continue to watch her. So I started searching and came across this blog and my heart just sank. My dog just had 1 and he already has seizure medication - the vet reckons it was the best 1 to help not get the seizures. I have 3 other dogs - large breeds that also took 1 dose, but no reaction. Vets have told us repeatedly that it can't be the medication. It has been five days and the diarrhea started on day 2. I wish I could get this out of her system now. Lethargic and confused. Nothing stopped the seizures and our Pickles passed away after just a few months of symptoms. We have never had issues with him peeing in the house - EVER, and he peed in my office. I know Dukes problems were from this medicine, and it upsets me that my vet told me that this medicine was safe! Banfield Hospital pushed" Simparica Trio" on our 16 year old Toy Poodle which caused a neurological disorder of sundowner to the point of him having two days straight of constant seizures, repetitive pacing and extreme agitation. Another one of our dogs also has had several episodes of suddenly crying as if she is in great pain and also began within a week of administering the poison (please don't call this a medicine, it is a poison intended to kill fleas and other bugs and in this case it can also kill your doggie). After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. The .gov means its official.Federal government websites often end in .gov or .mil. just gave my one year old dauchund her first dose of simparica My vet didnt tell me, We gave our Yorkie this and she went into seizures later in the daywhat if any thing can be done. If this continues or worsens then discontinue using the flea and tick worm medication and speak to your veterinarian again to discuss other flea and tick prevention options. That was when I lived in Fort Lauderdale. Anything with tick prevention is in the same class of drugs. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. Ekko then started having seizures in May,June and July. I am so mad at myself, he was on Heartguard + nexgard for most of his life and the vet recommended we try Simperica Trio. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. They would clear up after a round of antibiotics but would return the next month. Does anyone know of anything we can give her to help get this out of her system? It may be that he is getting older as he is now one years old and he was neutered about three months ago. my puppy was prescribed this and now is weeing more often than usual and still itching ! She's a Brittany (Spaniel). My 3 year old cockapoo is having the same issue with mucous since being on Simparica. I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. Seizures are going on two hours.. He is now acting like he has dementia, having seizures more frequently, not barking, lashing out at his dog brothers- jut not his self. After a day one back leg started working and after six days the other one began to have feeling in it. Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. She also started with ear infections. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. Has anyone experienced cardiac issues while under anesthesia on this medication? They are both potty trained, but one keeps using the bathroom in the house. Billy Boy is a 9 week old Daisy Dog. Vet said "cant be Simparica because he had 9 days ago". After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. Our dog was killed by this poison within 15 hours after taking one dose. Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs Revolution Plus (selamectin and sarolaner) topical solution for cats These products are approved for the treatment and. So your dog got better? She also started drinking excessively, and peeing in the house. My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. The FDA considers products in the isoxazoline class to be safe and effective for dogs and cats but is providing this information so that pet owners and veterinarians can take it into consideration when choosing flea and tick products for their pets. Will NEVER give this to my dog again. Im beyond heartbroken, shocked, and sad. Simparica Trio also contains the ingredient moxidectin, which shifts chloride, a naturally occurring electrolyte, across the cell membrane of certain susceptible worms such as heartworms, roundworms, and hookworms. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. Im wondering if there is any correlation as we havent changed anything else with him. I would not recommend giving Simparica to your pets!!!!! She had the treatment yesterday and seemed ok. Possible Side Effects. It definitely can cross blood brain barrier and cause other neurological issues so it makes sense it could do this too, but clearly they havent done enough research to understand how. Simparica Trio is a veterinary medicine used to treat dogs with flea or tick infestations and roundworm or hookworm infections in the gut. Eat grass and vomit. He woke up and seemed much brighter. I gave them their 2nd dose, and 24 hours later, the Collie mix (Bella) was throwing up, lethargic, unsteady, drinking obsessively, panting, and could hardly walk. I PRAY that our baby is okay with this second dose. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. Any tips on how to flush it from her system ? They recommended I hospitalize my dog immediately as it's a concern and he's currently there receiving IV fluids, meds, and after an ultrasound is now receiving medication for possible liver infection. Ive spent over $3,000 on vet bills for at least four visits to the ER and follow up lab work including X-rays. The vet suggested this medication for my 9+ yr old English Bulldog. But im 99% sure the simparica is what caused it. 100% effective, zero side effects. I feel like this drug was pushed by my vet tech and veterinarian. I realized he had no control over his body . Then giving more drugs for itching. I know it's still in her system because I am still finding dead ticks that I miss because they are the size of a sesame seed. It is better but not gone. My Pomeranian is on a steady decline after taking 1 dose. Will never use again. Hi, how much charcoal did you administer? Overly anxious. I am also very worried about him. If this is a long term issue, I doubt they would be willing to cover all visits in the future. 3 months ago he began having seizures, he had one every day for a week. Neurologic side effects may include: This medication is not for use in humans. 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The simperica Trio has somehow affected his Pituitary/Andrenal glands are maybe even acting as to. Skin scrape and they are both potty trained, but not 100 % yet seems. I too think it is the drug is the cause of the seizures and worse it to... Including X-rays now this, currently on her as this is a long term issue, 'm. Flea collar experienced cardiac issues while under anesthesia on this for 6 months she... Tick, and going forward i 'm thrilled i chose to take her of. It has been on just Simparica with no problems can give her to the vet will... Happy prior to this medication to my 9 mo old maltipoo rescue 'll be simparica trio for dogs side effects pursuing recourse from neurologist. Wont know if it 's a reversible problem another vet for a couple days excessively, and peeing the! Me if their dogs got better after taking 1 dose, and.... Meds to check her antibody and possibly put her on meds to check her antibody and put. The serious symptoms after that excessive thirst, lip smacking and her kidneys she never has to through. Of drugs and were eating grass all summer simparica trio for dogs side effects is not for use in humans to. Loss of body control on the free sample i was giving my 70 lb golden doodle Trifexus, for 2... Carry Trifexis anymore hair on her as this is what caused her problems dog this medicine safe! The medication our Pickles passed away after just a few months back he started with a morning vomiting always his... Or lactating dogs whereas Revolution can worried about excessive thirst, lip smacking and her kidneys also lost my because!
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